Methadone is a long-acting synthetic opioid used internationally in maintenance treatment for people who have developed opioid dependence. In Spain, around 58,000 people are currently in maintenance programs, many for over a decade. ICEERS leads the first-ever Phase II clinical trial on ibogaine as a tool to support tapering off methadone, conducted at Sant Joan de Reus University Hospital. This page gathers content on this substance, opioid dependence and research on ibogaine-assisted detoxification.