Death — as biological event, existential horizon, ritual passage and cultural construct — runs through many traditions of work with psychoactive plants and traditional medicines. From Indigenous funerary practices to research on the use of psychedelics in end-of-life care, palliative contexts and anxiety associated with terminal illness, this thread brings together a wide range of perspectives. ICEERS gathers here content addressing death, dying, grief and existential meaning in relation to its work.