The placebo is a methodological cornerstone of clinical research, used as a comparator in randomized, double-blind trials to isolate the specific effects of an intervention from expectation, context and natural variation. ICEERS has contributed to multiple randomized, placebo-controlled clinical trials with ayahuasca and cannabidiol in healthy volunteers and clinical populations, exploring effects on personality, emotion recognition, anxiety, social cognition and depression. This page gathers content related to placebo-controlled research featured on the ICEERS website.