Ibogaine is the main psychoactive alkaloid of Tabernanthe iboga, used for decades outside the conventional medical system to treat opioid and other substance dependencies. Its anti-addictive properties have drawn growing scientific attention, alongside serious cardiovascular safety concerns and complex ethical, legal and biocultural questions linked to its origin in Central African traditions. ICEERS gathers here clinical, regulatory and cultural content on ibogaine, including research on detoxification, harm reduction and protection of source communities.