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    All ICEERS’ studies are peer-reviewed, published in indexed and high-impact journals and follow the strictest methodological and ethical standards.

    ayahuasca alcohol use

    Effects of a Single Dose of Ayahuasca in Harmful Alcohol Use

    This study aimed to evaluate the effects of a single dose of ayahuasca on college students with harmful alcohol use. The trial included 11 male college students, who were administered ayahuasca in a controlled environment with psychological support.

    ayahuasca memory cognition

    Ayahuasca Preserves Cognitive Function and Improves Memory

    This study investigates the cognitive effects of long-term ayahuasca use among members of the Santo Daime church in Brazil, focusing on experienced users (over 20 years of use) and comparing them to beginner users (less than 3 years of use) and a control group of non-users.

    ayahuasca ibogaine

    Safety in Ayahuasca and Ibogaine Administration

    The research team designed guidelines for managing adverse scenarios in clinical trials involving ayahuasca and ibogaine. These include detailed protocols for participant screening and selection, medication management, and procedures during and after the experimental session.

    globalización ayahuasca globalization

    The Globalization of Ayahuasca

    This study offers an in-depth look at the globalization of ayahuasca, focusing on the case of a woman who migrated from the Amazon rainforest to Barcelona.

    ayahuasca alcohol

    Ayahuasca and Harmful Alcohol Use

    This study aimed to analyze subjective reports of university students with harmful alcohol use participating in a single-blind study evaluating the effects of one ayahuasca dose (1 mL/kg).

    psychedelic social club

    The Psychedelic Social Club

    The authors propose community or peer-based structures as a viable means to control the supply of psilocybin-containing mushrooms and ensure a safe environment for non-medical use.

    ayahuasca ritual uso brasil

    Clinical Use of Ayahuasca in Brazil

    This study explores the articulations between the ritual use of ayahuasca by Indigenous and religious communities, the scientific interest in its therapeutic effects and the hegemonic psychotherapeutic models built around hallucinogens.

    ayahuasca neural modulation ICEERS study research

    Neural Network Modulation of Ayahuasca

    This study focuses on neural network modulation by ayahuasca exclusively. It is a systematic review aimed to assess changes in brain anatomy and neural networks activation with acute, subacute, or chronic use of ayahuasca through neuroimaging techniques.

    ayahuasca adverse effects efectos adversos ICEERS study estudio

    Adverse Effects of Ayahuasca

    This study includes an exhaustive review of all the studies that have been published on the adverse effects of ayahuasca, with data taken from the Global Ayahuasca Survey..

    ayahuasca rapid antidepressant

    Ayahuasca as a Potentially Rapid Acting Antidepressant

    This study gathered data regarding the occurrence of adverse events in all reported randomized, placebo-controlled trials with healthy and clinical populations involving ayahuasca administration (n = 108 ayahuasca administrations).

    ayahuasca endocannabinoid system

    Effects of Ayahuasca on the Endocannabinoid System

    This study assessed endocannabinoid (anandamide, AEA; 2-arachidonoylglycerol, 2-AG) plasma levels in healthy volunteers and in volunteers with social anxiety disorder (SAD) after a single oral dose of ayahuasca or placebo.

    ayahuasca speech performance social anxiety habla discurso ansiedad social

    Ayahuasca and Speech Performance in Social Anxiety

    This study investigates the effects of ayahuasca in volunteers with social anxiety disorder in a randomized, single-dose, double-blind, placebo-controlled, parallel-group clinical trial. Volunteers participated in an experimental session that included a simulated public-speaking test.

    effects ayahuasca substance use disorders drugs ICEERS study

    Effects of Ayahuasca on Substance Use Disorders

    This study updated the previous systematic review evaluating quantitative preclinical and human studies assessing the efects of ayahuasca and its alkaloids on drug use and other psychological and cognitive measures related to substance use disorders.

    risk ayahuasca religion study ICEERS riesgos

    Risk Assessment of Ayahuasca Use in a Religious Context

    The aim of this study was to assess the risk profile of ayahuasca use in a religious context. After reviewing the literature to identify important concerns and common adverse effects, the authors developed an instrument that inquired about the frequency of the following effects: anxiety, diaphoresis, diarrhea, disorientation, distress, dizziness, drowsiness, dry mouth, headache, irritability, nausea, restlessness, shivers, tachycardia, tinnitus, tremor, and vomiting. 

    ayahuasca personality study ICEERS

    Effects of Ayahuasca on Personality

    This article presents data from two randomized, double-blind, placebo-controlled clinical trials that evaluated the effects of ayahuasca on personality traits in healthy volunteers. Considering the evidence of associated changes in personality in other classic hallucinogens, and the antidepressive and anxiolytic effects of ayahuasca, the hypothesis was that ayahuasca would produce increases in Openness and Conscientiousness scores and decreases in Neuroticism scores.

    ayahuasca recognition facial emotions study ICEERS iowaska

    Effects of Ayahuasca on the Recognition of Emotions

    The main objective of this pilot, proof-of-concept, randomized trial was to assess the effects of ayahuasca on the recognition of emotion in facial expressions (REFE), hypothesizing that ayahuasca would modify this parameter.

    Shipibo ayahuasca well-being ICEERS study Beckley

    Shipibo Ceremonial Use of Ayahuasca for Well-Being

    Over the course of one year, this prospective, observational non-controlled study, supported by ICEERS and the Beckley Foundation, examined the well-being and quality of life of 200 participants in a Shipibo healing program with ayahuasca, conducted by traditional healers. The results suggested that the Indigenous Shipibo healing work with ayahuasca has value to improve long-term well-being and quality of life for Westerners.

    adverse psychological reactions effects ayahuasca use naive study ICEERS

    Adverse Reactions in First-Time Ritual Ayahuasca Users

    This article provides a case series of challenging psychological experiences found in a subsample of subjects from a previously published study in which the authors recruited ayahuasca-naive participants and followed them for 6 months after their first ayahuasca use.

    ayahuasca mental health quality of life naïve users salud mental ICEERS

    Ayahuasca on Mental Health and Quality of Life

    Since ayahuasca use is expanding worldwide, the aim of this study was to observe the effects of ayahuasca on psychological and mental health variables in naïve users in order to help medical practitioners to understand possible adverse effects and potential therapeutic uses.

    ayahuasca iowaska grief death grieving mourn ICEERS study

    Therapeutic Potential of Ayahuasca in Grief

    This study investigated the long-term effects of ayahuasca in participants who were grieving the death of a loved one, following a sample of subjects with a history of grief who willingly attended ayahuasca ceremonies at an ayahuasca center in Peru.

    ayahuasca iowaska antidepressant antidepresivo ICEERS

    Ayahuasca as an Antidepressant

    This article reviews the previous preclinical, experimental and clinical studies available in the scientific literature in order to provide further translational evidence of the antidepressant effects of ayahuasca.

    ayahuasca public health study jungle ICEERS

    Ayahuasca and Public Health

    Assessing the health status of ayahuasca users has been challenging due to the limitations involved in randomized clinical trials and psychometric approaches. The main objective of this study is the implementation of an approach based on public health indicators.

    ayahuasca enhancement visual imagery study ICEERS imágenes

    Enhanced Visual Imagery with Ayahuasca

    In October 2016, the authors were contacted by a 39-year-old man, Scotty Enyart, who claimed that ayahuasca improved his aphantasia. He was diagnosed with poor visual imagery in elementary, middle, and high schools.

    psychological values therapeutic effect ayahuasca iowaska ICEERS study

    Psychological Variables in the Therapeutic Effect of Ayahuasca

    The underlying psychological processes related to the use of ayahuasca in a psychotherapeutic context are not yet well described in the scientific literature, but there is some evidence to suggest that psychological variables described in psychotherapies could be useful in explaining the therapeutic effects of the brew.

    ayahuasca hallucinogens psychedelics social anxiety

    Therapeutic Potential of Ayahuasca for Social Anxiety

    In the present article, we review basic and clinical evidence supporting the possible beneficial effects of ayahuasca (and other serotonergic or classical hallucinogens) in the treatment of mood and anxiety disorders in general, with a focus on social anxiety.

    ayahuasca mental health professionals healthcare salud mental

    Ayahuasca and Mental Health Professionals

    This article, intended for mental health professionals, reviews the most recent human studies about the effects of ayahuasca, a natural psychoactive concoction used for centuries by indigenous groups from Northwestern Amazonian countries.

    ayahuasca grief therapy study ICEERS

    Potential Use of Ayahuasca in Grief Therapy

    The principal objective of this study was to explore the effects of ayahuasca on grief and to compare its potential therapeutic benefits with peer-support groups in a sample of grieving people. This study was a mixed method, cross-sectional study, using an online survey method.

    ayahuasca psychosis DMT iowaska ICEERS study

    Ayahuasca, DMT, and Psychosis

    The aim of this study was to present a systematic review of the cases in which psychotic events occurred after the acute effects of ayahuasca and DMT. The authors attempted to identify all studies available to review up to 16 August 2016 in which a possible association between ayahuasca/DMT intake and psychotic disorders was reported.

    Mystical Experience Questionnaire study ICEERS

    The Factor Structure of the Mystical Experience Questionnaire

    This letter to the editor, published in Human Psychopharmacology Clinical and Experimental vol. 32, is a reply to the commentary by Barret and Griffiths (2016) regarding our Spanish version of the MEQ‐30 (Bouso, Pedrero‐Pérez, Gandy, & Alcazar‐Corcoles, 2016).

    research on ayahuasca review study ICEERS

    The Current State of Research on Ayahuasca

    In recent decades, the use of ayahuasca — a β-carboline- and dimethyltryptamine-rich hallucinogenic botanical preparation traditionally used by Northwestern Amazonian tribes for ritual and therapeutic purposes — has spread from South America to Europe and the USA, raising concerns about its possible toxicity and hopes of its therapeutic potential. Thus, it is important to analyze the acute, subacute, and long-term effects of ayahuasca to assess its safety and toxicity.

    subjective effects hallucinogens psychedelics study ICEERS ayahuasca

    Measuring the Subjective Effects of Hallucinogens

    The subjective effects of psychedelic drugs are probably their most difficult aspect to measure. Therefore, we used novel psychometric data for the MEQ, HRS, and ARCI questionnaires, proposing preliminary new versions and/or alternative interpretations of the data.

    holding hands ayahuasca drug addiction ICEERS study

    Ayahuasca and the Treatment of Drug Addiction

    This study, entitled “Ayahuasca and the Treatment of Drug Addiction,” constitutes the chapter number 6 in the book The Therapeutic Use of Ayahuasca (pp. 95-109), published by Springer in November 2014 as part of a project called Psychoactive Plants and Public Health. Beatriz Caiuby Labate and Clancy Cavnar were the editors of this volume.

    ayahuasca drug dependency ICEERS study

    Ritual Ayahuasca Use on Drug Dependency

    This chapter presents preliminary data obtained at the Instituto de Etnopsicología Amazónica Aplicada (IDEAA), placed at the Brazilian Amazon basin. The aim was to describe an observational study on the variations on personality, psychopathology, and neuropsychological measures in individuals treated with ayahuasca in this setting.

    root tree nature effects of ayahuasca ICEERS study

    Acute Effects of Ayahuasca on Neuropsychological Performance

    Ayahuasca, a South American psychotropic plant tea containing the psychedelic 5-HT2A receptor agonist N,N-dimethyltryptamine, has been shown to increase regional cerebral blood flow in prefrontal brain regions after acute administration to humans. Despite interactions at this level, neuropsychological studies have not found cognitive deficits in abstinent long-term users.

    ritual users ayahuasca ICEERS study

    Psychopathology and Life Attitude Among Ritual Users of Ayahuasca

    To study the impact of repeated ayahuasca use on general psychological well-being, mental health and cognition, here we assessed personality, psychopathology, life attitudes and neuropsychological performance in regular ayahuasca users (n = 127) and controls (n = 115) at baseline and 1 year later.

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